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Endocrine Abstracts

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ea0016p207 | Diabetes and cardiovascular diseases | ECE2008

Elevated plasma fatty acid levels are associated with myocardial triglyceride accumulation and diastolic dysfunction in type 2 diabetes mellitus which can be reversed by acipimox

Smit Joahnnes , Hammer Sebastiaan , van der Meer Rutger , de Roos Albert , Lamb Hildo , Romijn Johannes

Background: Although it has been conceived that type 2 diabetes mellitus (DM2) is associated with increased myocardial triglyceride (TG) accumulation, it is unknown whether this can be influenced by modifying plasma non-esterified fatty acids (NEFA) levels. We therefore determined in uncomplicated DM2 whether modifications in plasma NEFA influence myocardial TG content and myocardial function.Research design and methods: Myocardial TG content and left ve...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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